Mitral valve ring calcium seen by chance on a scan
An echocardiogram or chest CT done for another reason may mention mitral annular calcification: calcium in the ring (annulus) that holds the mitral valve, the valve between the left upper and lower heart chambers. UK radiology groups say it is common and in many cases has no clinical significance. (BSCI/BSTI 2021) This page covers what it means and what checks usually follow, not treatment.
The main guidance
- BSCI/BSCCT and BSTI consensus (UK, 2021): review the heart on every chest CT where it is seen. Calcium in the mitral leaflets or ring can be graded as none, mild, moderate or severe. People with calcium on the leaflets may need more assessment of how the valve works, while ring calcium "is rarely a therapeutic target". (BSCI/BSTI 2021)
- NICE NG208 (UK, 2021): bases the echocardiogram decision on a heart murmur, with age (especially over 75), family history and medical history as factors. It does not mention calcium seen on a scan. (NICE NG208)
- KDIGO (kidney guideline, 2017): for people with moderate or worse chronic kidney disease (stage G3a to G5D), an echocardiogram can be used to look for valve calcium, and known valve calcium suggests they be considered at highest heart risk. (KDIGO 2017)
How common it is
It becomes more common with age. (MESA 2010)(MedlinePlus) Figures depend on the scan and the group studied:
| Group and scan | Share with ring calcium |
|---|---|
| Routine chest CT (UK consensus, leaflet or ring) | About 8% (BSCI/BSTI 2021) |
| Heart CT, adults 45 to 84 without heart disease (MESA, US) | 9% overall: 12% white, 10% Hispanic, 7% Black and 5% Chinese adults (MESA 2010) |
| Echocardiogram, older community adults (Framingham, US) | 10.3% of men and 15.8% of women (Framingham 1992) |
| Echocardiogram for a medical reason (Mayo Clinic, US) | 23%; average age 75, compared with 60 in those without it (Kato 2022) |
In MESA, older age, being a woman, diabetes and a higher body mass index were linked to it. (MESA 2010) A hospital study found women had more extensive ring calcium than men, and end-stage kidney disease was linked to moderate or severe calcium in both. (Seo 2021)
Kidney disease
In the Framingham study, people with chronic kidney disease (an eGFR below 60) had 60% higher odds of mitral ring calcium, after allowing for age, blood pressure, cholesterol, diabetes, smoking and other factors. Having both was linked to three times the risk of death, after allowing for age and sex. (Framingham 2006) For the kidney tests themselves, see kidney test results and kidney disease screening.
Its tie to heart disease and stroke
- Heart disease: over 16 years in Framingham, ring calcium was linked to a 1.5 times higher risk of new heart and blood vessel disease, and each extra millimetre of calcium to about 10% more risk. The authors call heart calcium "a marker of increased CVD risk". (Framingham 2003)
- Stroke: in older Framingham adults it was linked to about twice the risk of stroke over 8 years, separate from the usual stroke risk factors. The authors say it is unknown whether it adds to stroke risk itself or is only a marker. (Framingham 1992) A study of American Indian adults without heart disease found a similar link. (Strong Heart 2005)
- The valve itself: in the Mayo Clinic study, a narrowed mitral valve (mitral stenosis) was found in 6.6% of people with ring calcium, compared with 0.5% without it, and a moderate or worse leak in 9.5% compared with 6.1%. (Kato 2022)
What usually comes next
- Heart risk factors: because the finding is tied to heart and stroke risk, the routine checks for your age matter, such as blood pressure, cholesterol and, where advised, kidney tests. (Framingham 2003)(MESA 2010)
- An echocardiogram: NICE ties it to a heart murmur heard by a doctor. (NICE NG208) UK radiology groups say leaflet calcium on a CT may need a look at how the valve works. (BSCI/BSTI 2021) NICE suggests considering an echocardiogram every 3 to 5 years for adults with mild mitral stenosis. (NICE NG208)
- Symptoms: the NHS says that if you have symptoms of heart valve disease a GP will listen to your heart and may arrange an echocardiogram. (NHS)
What the finding does and does not show
- On a CT it is a picture of calcium, not a test of how the valve works. UK radiology groups also warn that it should not be mistaken for calcium in a nearby heart artery (the left circumflex). (BSCI/BSTI 2021)
- It can grow: in a hospital study of people with mild or moderate ring calcium who had a second echocardiogram 18 to 36 months later, 31% had worsened by more than one grade. (Lee 2023)
- For calcium on a different valve or in the main artery, see aortic valve calcium seen by chance on CT and aortic calcification seen by chance. For a small leak reported on an echo, see mild leaky heart valve.
NHS, when to get help for possible heart valve symptoms: (NHS)
See a GP if:
- you're feeling short of breath regularly
- you feel tired, weak or dizzy when doing normal activities
- you have heart palpitations that keep coming back, last longer than a few minutes or are getting worse
- you have swollen ankles or feet
- you have chest pain that comes and goes
Call 999 or go to A&E if:
- you're struggling to breathe
- you have sudden chest pain that spreads to your arms, back, neck or jaw, or lasts more than 15 minutes
- you have chest pain with shortness of breath or heart palpitations
In the US, the emergency number is 911.
Routine age-based screening
A finding on a scan does not replace the routine screenings for your age. See heart screenings by age and atrial fibrillation screening.
Where they differ:
- How much it matters. UK radiology groups say ring calcium is often incidental without clinical significance and rarely a treatment target. (BSCI/BSTI 2021) Large US studies link it to higher rates of heart disease, stroke and death after allowing for other risk factors. (Framingham 2003)(Framingham 1992)(Kato 2022)
- Kidney disease. KDIGO suggests people with moderate or worse chronic kidney disease and known valve calcium be considered at highest heart risk. (KDIGO 2017) The UK radiology consensus does not set a different approach for them. (BSCI/BSTI 2021)
- What triggers an echocardiogram. NICE bases it on a murmur and does not cover scan findings. (NICE NG208) The UK radiology consensus points to calcium on the leaflets, not the ring. (BSCI/BSTI 2021)
Your doctor decides what your result means for you.
Questions people ask
Is calcium in the mitral valve ring dangerous?
Often it causes no problem by itself. UK radiology groups say it is often an incidental finding without clinical significance and is rarely a target for treatment. Large studies link it to a higher chance of heart disease and stroke, and the Framingham authors call it a marker of raised heart risk. (BSCI/BSTI 2021) (Framingham 2003)
How common is it?
Common, and more so with age. It is seen on about 8% of routine chest CT scans, on 9% of heart CT scans in adults aged 45 to 84 without heart disease, and on 23% of people having an echocardiogram in one large hospital study. (BSCI/BSTI 2021) (MESA 2010) (Kato 2022)
Does it mean my mitral valve is not working?
Usually not. In one large hospital study, a narrowed mitral valve was found in 6.6% of people with ring calcium, compared with 0.5% without it. UK radiology groups say calcium on the valve leaflets is the finding more likely to need a look at how the valve works. (Kato 2022) (BSCI/BSTI 2021)
Why does kidney disease matter?
In the Framingham study, people with chronic kidney disease had 60% higher odds of mitral ring calcium after allowing for other risk factors. The kidney guideline group KDIGO suggests people with moderate or worse chronic kidney disease and known valve calcium be considered at highest heart risk. (Framingham 2006) (KDIGO 2017)
Will I need an echocardiogram?
Not always. NICE bases the decision on a heart murmur heard when a doctor listens to your chest, along with things such as age over 75. If a CT is the scan that showed the calcium, an echocardiogram shows how the valve works. Your doctor decides. (NICE NG208) (NHS)
Related
- Enlarged left atrium seen by chance on an echo
- Aortic valve calcium seen by chance on a CT scan
- Mild leaky heart valve seen on an echocardiogram
- Aortic calcification seen by chance on an X-ray or CT
- Thick heart muscle seen by chance on an ECG or echo
- Enlarged heart seen by chance on a chest X-ray
- Small fluid around the heart seen by chance on a scan
- Kidney test results
- Heart screenings by age
- After an abnormal screening result
- Screenings by age and gender